Pharmacology & Physiology
Recent Publications
E. Zakharian, C. Cao. T. Rohacs,. Intracellular ATP supports TRPV6 activity via lipid kinases and the generation of PtdIns(4,5)P2, in press, FASEB J
E. Zakharian, C. Cao, T. Rohacs, Gating of TRPM8 channels activated by cold and chemical agonists in planar lipid bilayers, J. Neurosci 2010, 30(37):12526-34
T. Rohacs, Phosphoinositide regulation of non-canonical Transient Receptor Potential channels, Cell Calcium, 2009, 45: 554–565
E. Zakharian, B. Thyagarajan, R. J. French, E. Pavlov, and T. Rohacs: Inorganic polyphosphate modulates TRPM8 channels, PLoS ONE, 2009;4(4):e5404
Thyagarajan B, Benn BS, Christakos S, Rohacs T. Phospholipase C mediated regulation of TRPV6 channels: implications in active intestinal Ca2+ transport. Mol.Pharmacol. 2009. 75(3):608-16
T. Rohacs, B. Thyagarajan, V. Lukacs: Phospholipase C mediated modulation of TRPV1 channels, Molecular Neurobiology, 2008, 37(2-3):153-63
Thyagarajan, B., Lukacs, V., and Rohacs, T. Hydrolysis of phosphatidylinositol 4,5-bisphosphate mediates calcium induced inactivation of TRPV6 channels. J.Biol.Chem 2008. 283:14980-14987
T. Rohacs, Bernd Nilius: Regulation of Transient Receptor Potential (TRP) channels by phosphoinositides Pflugers Archive 455(1):157-68, 2007
Viktor Lukacs, Baskaran Thyagarajan, Peter Varnai, Andras Balla, Tamas Balla, Tibor Rohacs: Dual regulation of TRPV1 by phosphoinositides J Neurosci 27 (26):7070-80. 2007
T. Rohacs: PIP2 regulation of TRP channels Pflugers Archive 453(6):753-62, 2007
P. Varnai, B. Thyagarajan, T. Rohács, and T. Balla. Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact cells. J. Cell. Biol. 2006, 175: 377-
T. Rohács, C.M.B. Lopes, I. Michailidis, D.E Logothetis: PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain, Nature Neuroscience 8:626-634, 2005
T. Rohács: Teaching Resource. TRP channels, Science STKE 2005(282):tr14, 2005