1. Name of activity: Nutrition

2. Project leader and email address: John D. Bogden, Ph.D. bogden@umdnj.edu

3. Brief statement of mission and/or vision:

A. Guided by national guidelines, to train medical students in clinical and public health nutrition and thereby enable them to use nutrition knowledge and concepts in the diagnosis and treatment of patients and the prevention of disease.

B. To conduct laboratory, clinical, and public health research in nutrition that focuses on enhancing knowledge of disease processes and prevention.

4. Collaborators, staff and faculty by name and email:

Herman Baker, Ph.D., Adjunct Professor, bakerhe@umdnj.edu

Francis W. Kemp, B.S., Research-Teaching Specialist II, kemp@umdnj.edu

Donald B. Louria, M.D., Professor, louriado@umdnj.edu

5. Specifics about activity:

Teaching:

Second year NJMS course: Clinical and Public Health Nutrition

M.S. in Clinical Nutrition Program: Vitamin and Mineral Nutrition

TEXTBOOK: JD Bogden and LM Klevay: Editors, Clinical Nutrition of the Essential Trace Elements and Minerals: The Guide for Health Professionals . Humana Press, Totowa, NJ, 2000. ISBN: 0-89603-598-0, 415 pages.

Research:

Dr. Baker: Vitamin nutrition

Dr. Bogden: Mineral and trace element nutrition and toxicology

Dr. Louria: Nutrition in prevention of disease

Mr. Kemp: Laboratory methods in trace element and mineral nutrition

6. Selected representative publications and presentations from project:

SELECTED PUBLICATIONS

S Han, W Li, U Jamil, K Dargan, M Orefice, FW Kemp , and JD Bogden : Effects of weight loss and exercise on the distribution of lead and essential trace elements in rats with prior lead exposure. Environ Health Perspect , 107:657-662, 1999.

S Han, DH Pfizenmaier, E Garcia, ML Eguez, M Ling, FW Kemp , and JD Bogden : Effects of lead exposure before pregnancy and dietary calcium during pregnancy on fetal development and lead accumulation. Environ Health Perspect 108:527-531, 2000.

JD Bogden, FW Kemp, S Han, W Li, K Breuning, T Denny, JM Oleske, J Lloyd, H Baker, G Perez, J Skurnick, and DB Louria: Status of selected nutrients and progression of human immunodeficiency virus type 1 infection. Amer J Clin Nutr . 72:809-815, 2000.

DB Louria, JH Skurnick, P Palumbo, JD Bogden , C Rohowsky-Kochan, TW Denny, and CA Kennedy: HIV heterosexual transmission: a hypothesis about an additional potential determinant. International J Infectious Diseases , 4:110-116, 2000.

JD Bogden and LM Klevay: Editors, Clinical Nutrition of the Essential Trace Elements and Minerals: The Guide for Health Professionals . Humana Press, Totowa, NJ, 2000. ISBN: 0-89603-598-0, 415 pages.

DC Kossor, S Han, FW Kemp , RW Slauter, D Serota, D Rajaskarian, G Walter, N Milner, A Davidovitch, and JD Bogden: Administration of an oral antibiotic selectively alters copper nutriture in male rats. J Nutr , 131:3247-3250, 2001.

FW Kemp, J DeCandia, W Li, K Bruening, H Baker, D Rigassio, A Bendich, and JD Bogden: Relationships between immunity and dietary and serum antioxidants, trace metals, B vitamins, and homocysteine in elderly men and women. Nutrition Research , 22:45-53, 2002.

MF Sowers, TO Scholl, G Hall, ML Jannausch, FW Kemp, X Li, and JD Bogden: Lead in breast milk and maternal bone turnover. Am J Obstet Gynecol , 187:770-776, 2002.

MF Sowers, T Scholl, M Jannausch, W Li, FW Kemp, and JD Bogden: Blood lead concentrations and pregnancy outcomes. Archives Environ Health, 57:489-495, 2002.

W Li, S Han, TR Gregg, FW Kemp, DB Louria, A Siegel and JD Bogden: Lead exposure potentiates predatory attack behavior in the cat. Environ Research, 92:197-206, 2003.

JD Bogden: Influence of zinc on immunity in the elderly. J Nutr Health Aging, 8: 48-54, 2004.

JD Bogden and DB Louria: Nutrition and immunity in the elderly. In: Dietary Enhancement of Human Immune Functions, D Hughes, A Bendich, and LG Darlington, Editors, Humana Press, Totowa, NJ, 2004, pp. 79- 101.

M Kimura, X Lu, J Skurnick, G Awad, JD Bogden , FW Kemp , and A Aviv: Potassium chloride supplementation diminishes platelet reactivity in humans. Hypertension , in press.

A Stagnaro-Green, X Chen, JD Bogden, TF Davies, and TO Scholl: The thyroid and pregnancy: a novel risk factor for very preterm delivery. Thyroid , in press.

JD Bogden and DB Louria: Micronutrients and immunity in older people. In: Preventive Nutrition, 3rd edition. A Bendich and R Deckelbaum, Editors, Humana Press, Totowa, NJ, 2005, in press.

SELECTED RECENT PRESENTATIONS :

JD Bogden: Multivitamins and immunity. Presented at conference on Multivitamins and Public Health: Exploring the Evidence, Washington, DC, October 1-2, 2003, ( invited discussion leader/lecturer) .

FW Kemp, W Li, Y Berry, P Wenger, A Davidow, V Jacobs-Andrews, M Badie, D Louria, and JD Bogden: Dietary calcium and blood lead in urban children in the northeastern United States. Presented at FESTEM international symposium on Trace Elements in Medicine and Biology, Munich, Germany, May 14, 2004 (recognized as one of the 6 best posters presented at the meeting).

JD Bogden: Trace elements and the immune system: experimental and clinical aspects. Plenary lecture presented at FESTEM international symposium on Trace Elements in Medicine and Biology, Munich, Germany, May 15, 2004 ( invited lecturer ).

DP Vassilev, SM Marcus, K Ayyanathan, V Ciuffo, JD Bogden, FW Kemp, B Ruck, T Jennis, N Jani, and WH Halperin: Case of elevated blood lead in a South Asian family that has used sindoor as a food coloring. Presented at North American Congress of Clinical Toxicology meeting, Seattle, WA, September 13, 2004.

A Stagnaro-Green, X Chen, JD Bogden , TF Davies, and TO Scholl: The thyroid and pregnancy: a novel risk factor for very preterm delivery. Presented at American Thyroid Association meeting, Vancouver, BC, October, 2004.

JD Bogden: The environment and health: the paradigm of lead poisoning. Presented at Premedical Honors Program 2004, Newark, NJ, October 13, 2004 ( invited lecturer )

7. Other related websites:

Limited access website (UMDNJ WebCT) for the course Clinical and Public Health Nutrition

8. Opportunities for students: Laboratory, clinical, and field research:

More than 40 student participants to date.

9. Opportunities for volunteers: Laboratory, clinical, and field research.

10. Hidden text and keywords:

Hidden Text: Tufts University, Harvard University, University of California at Davis, Rutgers University, Cook College

Keywords: nutrition, clinical nutrition, public health nutrition, community nutrition, vitamins, minerals, trace elements, obesity, lead poisoning, calcium, vitamin D, zinc

Date revised: 3/30/05