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Departments
> Preventive Medicine & Community Health
tbcontrol
1. Activity: Tuberculosis Epidemiology and Surveillance
2. Faculty:
a. Amy Davidow, Ph.D.; davidoal@umdnj.edu
b. Other faculty:
- Marian Passannante, Ph.D. passanna@umdnj.edu
- Lee B. Reichman, M.D. reichmlb@umdnj.edu
- Bonita Mangura, M.D., mangurbt@umdnj.edu
(Dept. of Medicine)
3. Missions:
Reducing tuberculosis morbidity and mortality in the United
States which has seen a rise in tuberculosis in the 1980's after decades of
increasing declines; understanding the epidemiology of tuberculosis in New Jersey
and in the United States; conducting research on the improvement of treatment
completion; collaborating with bench scientists on promising new methods of
estimating prevalence of M. tuberculosis infection and improved diagnosis of
active disease
4. Specifics about activity:
a. TB Epidemiologic Studies Consortium (A Davidow, LB
Reichman). This is a 22 site consortium of academic institutions and health
departments funded by the Centers for Disease Control and Prevention (CDC).
On-going studies include:
- Enhanced surveillance to identify missed opportunities for prevention
of tuberculosis in the foreign-born (A. Davidow)
- A national genotyping registry for a molecular epidemiological analysis
of multidrug-resistant M. tuberculosis, (A. Davidow)
- Factors associated with acceptance of, adherence to and toxicity from
treatment for latent tuberculosis infection (TLTBI) and pilot study
of TLTBI effectiveness: phases 1 and 2 (A. Davidow)
- Prospective evaluation of immunogenetic and immunologic markers for
susceptibility to tuberculosis infection and progression from M. tuberculosis
infection to active TB (B. Mangura)
b. TB Surveillance Activities (M. Passannante)
- Develop community profiles for selected New Jersey counties using
TB surveillance data in collaboration with the New Jersey Department
of Health and Senior Services (E. Napolitano).
c. Conduct collaborative research projects with members of the NTBC (L. Reichman,
B. Mangura, C. Hayden)
Provide training in epidemiology for TB Control First Line Supervisors trained
at the NTBC.
5. Publications:
a. Davidow AL , Mangura BT, Napolitano EC, Reichman LB. Rethinking
the socio-economics and geography of tuberculosis among foreign-born residents
of New Jersey, 1994-1999. American Journal of Public Health 2003;93:1007-1012
b. Davidow AL , Mangura BT, Wolman MS, Bur S, Reves R, Thompson
V, Ford J, Reichler MR. Workplace contact investigations in the United States.
International Journal of Tuberculosis and Lung Disease 2003;7(12):S446-S452.
c. Basic Epidemiology for TB Program Staff Passannante
MR, Ahamed N. New Jersey Medical School National Tuberculosis Center.
d. Hayden CH, Mangura BT, Channer E, Paterson GE, Passannante
MR and Reichman LB. Tuberculin Testing and Treatment of Latent TB Infection
Among Lon-Term Jail Inmates, Journal of Correctional Health Care Vol 11 (1),
2004:99-117.
e. Yun LWH, Reves RR, Reichler MR, Bur SM, Thompson V, Mangura
B, Ford J. Outcomes of contact investigation among homeless persons with infectious
tuberculosis. International Journal of Tuberculosis and Lung Disease 2003;7(12):S405-S411.
f. DOT is not the entire answer - An operational cohort analysis,
Bonita T. Mangura MD, Eileen C. Napolitano BA, Marian R. Passannante PhD, Matthew
D. Sarrel BA,Reynard J. McDonald MD, Karen Galanowsky RN BSN MPH, Lee B. Reichman
MD MPH, The International Journal of Tuberculosis and Lung Disease , Aug 2002;6(8):654-61.
6. Opportunities for students and volunteers:
Contact Drs. Davidow or Passannante. The National Tuberculosis
Center is a fieldwork site for UMDNJ SPH students.
7. Links to other web sites:
- National Tuberculosis Center
- CDC Division of TB Elimination
- International Union Against Tuberculosis and Lung Disease
Date revised:
3/30/05
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