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Featured Graduate Student

Student Publications

2011

Dulal K., Zhang Z., and Zhu H. 2009. Development of a gene capture method to rescue a large deletion mutant of human cytomegalovirus. Journal of Virological Methods. Vol. 157(2), p.180-7.

Huang Y., Tang Q., Nguyen M., Dulal K., Wang W., and Zhu H. 2011. Histone deacetylase 3, not histone deacetylase 2, interacts with the major immediate early locus of human cytomegalovirus. Virology Journal. Vol. 8:151.

Lee SB, Lee CF, Ou DS, Dulal K, Chang LH, Ma CH, Huang CF, Zhu H, Lin YS, Juan LJ. 2011. Host-viral effects of chromatin assembly factor 1 interaction with HCMV IE2. Cell Research.Vol. 21(8), p.1230-47.

Ragunath, C., Shanmugam, M., Bendaoud, M., Kaplan, J. B. and Ramasubbu, N. (2011), Effect of a biofilm-degrading enzyme from an oral pathogen in transgenic tobacco on the pathogenicity of Pectobacterium carotovorum subsp. carotovorum. Plant Pathology. doi: 10.1111/j.1365-3059.2011.02509.x

Meriem Bendaoud, Evgeny Vinogradov, Nataliya V. Balashova, Daniel E. Kadouri,
Scott C. Kachlany, and Jeffrey B. Kaplan, 2011, Broad Spectrum Biofilm Inhibition
by Kingella kingae Exopolysaccharide. J Bacteriol. 2011 Aug; 193(15):3879-86.

Palmeri, D., Carroll KD., Gonzalez-Lopez, O., and Lukac, DM. (2011). Kaposi's Sarcoma-Associated Herpesvirus Rta Tetramers Make High-Affinity Interactions with Repetitive DNA Elements in the Mta Promoter To Stimulate DNA Binding of RBP-Jk/CSL. J. Virol. November 2011 85:11901-11915; published ahead of print 31 August 2011, doi:10.1128/JVI.05479-11

Utter CJ, Garcia SA, Milone J, and Bellofatto V. Poly(A)-specific Ribonuclease (PARN-1) function in stage-specific mRNA turnover in Trypanosoma brucei. Euk Cell, 2011. 10(9): p. 1230-40.

Mandal M, Marzouk AC, Donnelly R, Ponzio NM. Maternal immune stimulation during pregnancy affects adaptive immunity in offspring to promote development of TH17 cells. Brain, Behavior, and Immunity, 2011. Jul; 25(5):863-71.

Ganapathy Sriram, Charles Reichman, Ahmet Tunceroglu, Neil Kaushal, Tamjeed Saleh, Kazuya Machida, Bruce Mayer, Quinguan Ge, Jing Li, Peter Hornbeck, Charalampos Kalodimos and Raymond B. Birge (2011). Phosphorylation of Crk at Y251 in the RT Loop of the SH3C domain Promotes Abl Kinase Transactivation. Oncogene May 23, 2011 [Epub ahead of print]; doi:10.1038/onc.2011.170.

Andrew M. Parrott, Ganapathy Sriram, Yijun Liu and Michael B. Mathews (2011). Expression of Type II Chorionic Gonadotropin Genes Supports a Role in the Male Reproductive System. Mol. Cell Biol. Jan; 31 (2): 287-99. Epub 2010 Nov 15.

Yang Y, Ago T, Zhai P, Abdellatif M, Sadoshima J. Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. Circ Res. 2011 Feb 4;108(3):305-13. Epub 2010 Dec 23. Publication was highlighted at Editorial by Circulation Research, 2011.

Lin YR, Kim K, Yang Y, Ivessa A, Sadoshima J, Park Y. Regulation of longevity by Regulator of G-protein Signaling (RGS) protein, Loco. Aging Cell. 2011 Jan 21. doi: 10.1111/j.1474-9726.2011.00678.x.

Wu C, Parrott AM, Liu T, Jain MR, Yang Y, Sadoshima J, Li H. Distinction of thioredoxin transnitrosylation and denitrosylation target proteins by the ICAT quantitative approach. J Proteomics. 2011 Jun 17.

2010

Li Y, Messina C, Bendaoud M, Fine DH, Schreiner H, Tsiagbe VK., 2010, Adaptive
immune response in osteoclastic bone resorption induced by orally administered
Aggregatibacter actinomycetemcomitans in a rat model of periodontal disease. Mol
Oral Microbiol. 25(4): p. 275-92.

Spadavecchia, S., Gonzalez-Lopez, O., Carroll KD, Palmeri, D, and Lukac, DM. (2010). Convergence of Kaposi's Sarcoma-Associated Herpes virus Reactivation with Epstein-Barr Virus Latency and Cellular Growth Mediated by the Notch Signaling Pathway in Coinfected Cells , J. Virol. 84: 10488-10500.

Mandal M, Marzouk AC, Donnelly R, Ponzio NM. Preferential development of Th17 cells in offspring of immunostimulated pregnant mice. Journal of Reproductive Immunology, 2010. Dec; 87(1-2):97-100.

Ganapathy Sriram and Raymond B. Birge (2010). Emerging Roles for Crk in Human Cancer. Genes and Cancer 1 (11): 1132-1139.

Ago, T, Yang Y (co-1st author), Zhai, P, Sadoshima, J. Nifedipine Inhibits Cardiac Hypertrophy and Left Ventricular Dysfunction in Response to Pressure Overload. J Cardiovasc Transl Res. 2010 Aug;3(4):304-13. Epub 2010 May 1.

Takagi, H, Hsu, C.-P, Kajimoto, K, Shao, D, Yang Y, Maejima, Y, Zhai, P, Yeshia, G, Yamada, C, Zablocki, D, Sadoshima, J. Activation of PKN Mediates Survival of Cardiac Myocytes in the Heart during Ischemia/Reperfusion. Circ Res. 2010 Sep 3;107(5):642-9. Epub 2010 Jul 1.
Newnham CM, Hall-Pogar T, Liang S, Wu J, Tian B, Hu J, Lutz CS. 2010. Alternative polyadenylation of MeCP2: influence of cis-acting elements and trans-acting factors. In press, RNA Biology.

Ji Z, Lee JY, Pan Z, Jiang B, Tian B. 2009 Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development. PNAS 106:7028-7033

Jessica Cottrell and J. Patrick O'Connor 2009. Pharmacological inhibition of 5-lipoxygenase accelerates and enhances fracture-healing. Journal of Bone and Joint Surgery 91: 2653-2665.
Vanita Gupta and BJ Wagner 2009 Search for a functional glucocorticoid receptor in the mammalian lens. Exp Eye Res 88: 248-256.

2009

Yang, Y, Nakano, N, Sadoshima, J. Mir-206 Mediates Yap-induced Cardiac Hypertrophy: A Component of the Mammalian Hippo Pathway Regulating Cardiac Hypertrophy. Circulation. 2009;120:S758. AHA Scientific Sessions. Abstract 3197, Oral presentation, Florida, USA.

D’mello, V, Singh, S, Wu, Y, and Birge, RB. (2009). The urokinase activator receptor mediates efferocytosis of apoptotic cells. J. Biol. Chem. 284:17030-17038

D’mello, V and Birge, RB Regeneration after Death: Vav3 to the rescue. (2009). Blood. 113:5037-5038

Thyagarajan B, Benn B, Lukacs, V. Christakos, S, Rohacs, T. Phopholipase C mediated regulation of TRPV6 channels: implications in intestinal calcium absorption. Molecular Pharmacology 75: 608- 616 (2009).

Zhong, Y, Armbrecht, H.J. and Christakos, S. Calcitonin: a regulator of the 25-hydroxyvitamin D3 1 a hydroxylase gene. Journal of Biological Chemistry, in press (2009).

Ajibade, D, Benn, B. and Christakos, S. Mechanism of action of 1,25-dihydroxyvitamin D3 on intestinal calcium absorption and renal calcium transport. In Vitamin D: Physiology, Molecular Biological and Clinical Application. (M.F. Holick ed) Humana Press, Totowa, NJ, in press (2009).

2008

Benn, B.S., Ajibade, D., Porta, A., Dhawan, P., Hediger, M., Peng, J. B., Jiang, Y., Oh, G. T., Jeung, E. B., Lieben, L., Bouillon, R., Carmeliet, G. and Christakos, S. Active intestinal calcium transport in the absence of TRPV6 and calbindin-D9k. Endocrinology, 149: 3196 – 3205 (2008)
Raghuwanshi A, Joshi, S and Christakos, S Vitamin D and Multiple Sclerosis. J Cell Biochem 105: 338 – 343 (2008).

Guan, D., Altan-Bonnet N., Parrott A. M., Arrigo C. J.*, Li Q., Khaleduzzaman M., Li H., Lee C.G., Pe’ery T. and Mathews M.B. Nuclear factor 45 (NF45) is a regulatory subunit of complexes with NF90/110 involved in mitotic control. Mol. Cell. Biol . 28 (14), 4629-4641 (2008).

Liu, J., Ku, S.C.Y., Young, T.M*., Pe'ery, T., Mathews, M.B. and Chao, S-H. The 3'UTR of HIC mRNA improves the production of recombinant proteins in Chinese hamster ovary cells. J. of Biotechnology. 139, 152–155 (2009).

Pinky Kukreti, Kamalendra Singh, Amit Ketkar, and Mukund J. Modak, J. Biol. Chem., Vol. 283, Issue 26, 17979-17990, June 27, 2008. Identification of a New Motif Required for the 3'–5' Exonuclease Activity of Escherichia coli DNA Polymerase I (Klenow Fragment): The RRRY Motif is Necessary for the Binding of Single-Stranded DNSA Substrate and the Template Strand of the Mismatched Duplex

Manigrasso, MB and JP O’Connor. Comparison of fracture healing among different inbred mouse strains. Calcified Tissue International 82:465-474 (2008)

Cottrell, JA, M Meyenhofer, S Medicherla, L Higgins, and JP O’Connor. Analgesic effects of p38 kinase inhibitor treatment on bone fracture healing. PAIN in press.

Wannemacher, K.M., Terskiy, A., Bian, S., Yadav, P.N., Li, H., and Howells, R.D. Purification and mass spectrometric analysis of the kappa opioid receptor. Brain Res. 1230: 13-26, 2008.

J. Kyle Krady, Hsiao-Wen Lin, Christina M. Liberto, Anirban Basu Sergey G. Kremlev and Steven W. Levison* (2008) Ciliary Neurotrophic Factor And IL-6 Differentially Activate Microglia. Journal of Neuroscience Research, 86:1538-47. PMID 18214991.

Montgomery, SM Sirota A, Buzsáki G*.
Theta and gamma coordination of hippocampal networks during waking and rapid eye movement sleep. J Neurosci. 2008 Jun 25;28(26):6731-41.

Xiaolei Ma, Nazish Sayed, Padmamalini Baskaran, Annie Beuve*, Focco van den Akker. PAS-mediated dimerization of soluble guanylyl cyclase revealed by signal transduction histidine kinase domain crystal structure. J Biol Chem. 283(2):1167-78, 2008

Seip KM, Pereira M, Wansaw MP, Dziopa EI, Reiss JI, Morrell JI* (2008) Incentive salience of cocaine across the postpartum period of the female rat. Psychopharmacology 199:119-3

Pereira M, Seip KM, Morrell JI* (2008) Maternal motivation and its neural substrate across the postpartum period. In: The neurobiology of the parental mind. Amsterdam: Elsevier

Chernysh O , Condrescu M, Reeves JP. (2008) Sodium-dependent inactivation of sodium/calcium exchange in transfected Chinese hamster ovary cells. Am J Physiol Cell Physiol.295(4):C872-82.

Clarke RJ, Högnason K , Brimacombe M, Townes-Anderson E.(2008) Cone and rod cells have different target preferences in vitro as revealed by optical tweezers. Mol Vis. 14:706-20.

Colella M, Grisan F, Robert V, Turner JD , Thomas AP, Pozzan T. (2008) Ca 2+ oscillation frequency decoding in cardiac cell hypertrophy: role of calcineurin/NFAT as Ca 2+ signal integrators. Proc Natl Acad Sci U S A. 105:2859-64.

Lu X, Zheng R , Gonzalez J, Gaspers L, Kuzhikandathil E, Peluffo RD. (2008) L-lysine uptake in giant vesicles from cardiac ventricular sarcolemma: two components of cationic amino acid transport. Biosci Rep. 2008 Nov 25.

Ma X, Sayed N, Baskaran P, Beuve A, van den Akker F. (2008) PAS-mediated Dimerization of Soluble Guanylyl Cyclase Revealed by Signal Transduction Histidine Kinase Domain Crystal Structure. J Biol Chem. 283:1167-1178.

Rohacs T, Thyagarajan B, Lukacs V . (2008) Phospholipase C mediated modulation of TRPV1 channels. Mol Neurobiol. 37:153-63.

Sayed N , Kim DD, Fioramonti X, Iwahashi T, Durán WN, Beuve A. (2008) Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate tolerance. Circ Res.103:606-14.

Teichert RW, Garcia CC , Potian JG, Schmidt JJ, Witzemann V, Olivera BM, McArdle JJ. (2008) Peptide-toxin tools for probing the expression and function of fetal and adult subtypes of the nicotinic acetylcholine receptor. Ann N Y Acad Sci. 1132:61-70.

Thyagarajan B, Lukacs V , Rohacs T. (2008) Hydrolysis of phosphatidylinositol 4,5-bisphosphate mediates calcium-induced inactivation of TRPV6 channels. J Biol Chem. 283:14980-7.

Zhou Z, Sayed N , Pyriochou A, Roussos C, Fulton D, Beuve A, Papapetropoulos A. (2008) Protein kinase G phosphorylates soluble guanylyl cyclase on serine 64 and inhibits its activity. Arterioscler Thromb Vasc Biol. 28:1803-10.

2007

Yang, Y, Ago, T, Sadoshima, J. Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy through Upregulation of miR-98. Circulation. 2007;116:II_248. AHA Scientific Sessions. Abstract 1220, Oral presentation, Florida, USA.

Christakos, S., Dhawan, P., Peng, X., Obukhov, A. G., Nowycky, M. C., Benn, B. S., Zhong, Y, Liu, Y. and Shen, Q. New insights into the function and regulation of vitamin D target proteins. Journal of Steroid Biochemistry and Molecular Biology 103: 405-410 (2007)

Christakos, S., Dhawan, P., Benn, B.S., Porta, A., Hediger, M., Oh, G. T., Jeung, E. B., Zhong, Y., Ajibade, D., Dhawan, K. and Joshi, S. Vitamin D: molecular mechanism of action. Ann N.Y. Acad Sci. 1116:340 –348 (2007).

Xiaolei Ma, Nazish Sayed, Annie Beuve*, Focco van den Akker.: NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism. EMBO J. 26: 578-588, 2007

Nazish Sayed, Padmamalini Baskaran, Xiaolei Ma, Focco van den Akker, Annie Beuve*. Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation. Proc Natl Acad Sci. 104(30):12312-7, 2007

Needle E, Piparo K, Cole D, Worrall C, Whitehead I, Mahon G, Goldsmith LT*. 2007. Protein kinase A-independent cAMP stimulation of progesterone in a luteal cell model is tyrosine kinase dependent but
phosphatidylinositol-3-kinase and mitogen-activated protein kinase
independent. Biol Reprod. 2007 Jul;77(1):147-55. Epub 2007 Mar 28.

Rodriguez PL, Sahay S, Olabisi OO and Whitehead IP* (2007) ROCK I-mediated
activation of NF-kappaB by RhoB. Cell Signal. 19, 2361-2369.

Tibrewal, N, Lu, Tong, Li, Hong, and R. B. Birge* (2007). Biochemical and Biophysical Properties of the Phosphatidylserine receptor gene product. (Epub, Mol Cell
Biochemistry).

Kar, B, Singh, S., Reichman, C, O'Connor, JP, and R. B. Birge* (2007). Pro-apoptotic function of nuclear Crk II adaptor protein. (Epub, Biochemistry).

Hague LK, Hall-Pogar T, Lutz CS*. (2007) In vivo methods to assess
polyadenylation. In, Methods in Molecular Biology, J Wilusz, ed. In press.

Wannemacher KM, Yadav PM, Howells RD*. 2007. A select set of opioid ligands induce up-regulation by promoting the maturation and stability of the rat kappa opioid receptor in human embryonic kidney 293 cells. Journal of Pharmacology and Experimental Therapeutics, In press.

Greco SJ, Zhou C, Ye JH, Rameshwar P* (2007) An interdisciplinary approach and characterization of neuronal cells transdifferentiated from human mesenchymal stem cells. Stem Cells Dev (in press).

Greco SJ, Rameshwar P (2007) Enhancing effect of IL-1a on neurogenesis from adult human mesenchymal stem cells: Implication for inflammatory mediators in regenerative medicine. J Immunol 179:3342.

Greco SJ, Smirnov S, Murthy R, Rameshwar P* (2007) Synergy between RE-1 Silencer of Transcription (REST) and NFêB in the repression of the neurotransmitter gene Tac1 in human mesenchymal stem cells: Implication for microenvironmental influence on stem cell therapies. J Biol Chem (in press).

Greco SJ, Rameshwar P* (2007) miRNAs regulate synthesis of the
neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells. Proc Nat Acad Sci USA (in press).

Greco SJ, Liu K, Rameshwar P* (2007) Functional similarities among genes regulated by OCT4 in human mesenchymal and embryonic stem cells. Stem Cells (in press).

Katarzyna A. Trzaska, Eldo V. Kuzhikandathil and Pranela Rameshwar* Specification of a Dopaminergic Phenotype from Adult Human Mesenchymal Stem Cells DOI: 10.1634/stemcells.2007-0212
Stem Cells published online Jul 26, 2007;

Wang Q, Young TM, Mathews MB*, Pe'ery T*. Developmental regulators containing the I-mfa domain interact with T cyclins and
Tat and modulate transcription. J Mol Biol. 2007 Mar 30;367(3):630-46. Epub 2007 Jan 12.

Hall-Pogar T, Liang S, Hague LK, Lutz CS* 2007. Specific trans-acting proteins interact with auxiliary RNA polyadenylation elements in the COX-23' UTR. In press, RNA.

Dhar M , Sepkovic DW, Hirani V, Magnusson RP, Lasker JM. (2007) Omega oxidation of 3-hydroxy fatty acids by the human CYP4F subfamily enzyme CYP4F11. J Lipid Res. Dec 7; [Epub ahead of print]

Do T , Kerr B, Kuzhikandathil EV. (2007) Brain-derived neurotrophic factor regulates the expression of D1 dopamine receptors. J Neurochem. 100:416-428.

Do T , Sun Q, Beuve A, Kuzhikandathil EV.(2007) Extracellular cAMP inhibits D1 dopamine receptor expression in CAD catecholaminergic cells via A2a adenosine receptors. J Neurochem. 101:619-631.

Kaushik R, Rosenfeld CA, Sultatos LG. (2007) Concentration-dependent interactions of the organophosphates chlorpyrifos oxon and methyl paraoxon with human recombinant acetylcholinesterase. Toxicol Appl Pharmacol . 221:243-250.

Lukacs V , Thyagarajan B, Varnai P, Balla A, Balla T, Rohacs T. (2007) Dual regulation of TRPV1 by phosphoinositides. J Neurosci. 27:7070-7080.

Ma X, Sayed N , Beuve A, van den Akker F. (2007) NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism. EMBO J. 26:578-88.

Reeves JP, Condrescu M, Urbanczyk J , Chernysh O . (2007) New modes of exchanger regulation: physiological implications. Ann N Y Acad Sci . 1099:64-77.

Sayed N, Baskaran P, Ma X, van den Akker F, Beuve A. (2007) Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation. Proc Natl Acad Sci U S A 104:12312-12317.

Westrich L , Kuzhikandathil EV. (2007) The tolerance property of human D3 dopamine receptor is determined by specific amino acid residues in the second cytoplasmic loop. Biochim Biophys Acta. 1773:1747-1758.