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syllabus

Symposium on Human Variation:
A Driver of Personalized Medicine

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Syllabus

Thursday, January 29, 2009

8:15 a

Registration/ Continental Breakfast

9:00 a

Robert L. Johnson, FAAP, MD

The Sharon and Joseph L. Muscarelle Endowed Dean (Interim) and Professor, Department of Pediatrics, UMDNJ-New Jersey Medical School, Newark, NJ

Opening Remarks

9:05 a

Peter P. Tolias, PhD (Chair/Program Director)

Executive Director of the Institute of Genomic Medicine, Research Director of the Autism Center and Professor of Pediatrics, UMDNJ-New Jersey Medical School, Newark NJ; Adjunct Professor, Dept. of Molecular Genetics, Microbiology & Immunology, UMDNJ-Robert Wood Johnson Medical School, Piscataway NJ.

Welcome

9:15 a

Arnold J. Levine, PhD (Keynote Speaker)

Professor, The Institute for Advanced Study, Princeton NJ and The Cancer Institute of New Jersey, New Brunswick, NJ

Single Nucleotide Polymorphisms in the p53 Pathway

10:15 a

Break

10:45 a

 

Stuart A. Aaronson, MD (Invited Speaker)

Jane B. and Jack R. Aron Professor and Chairman of the Department of Oncological Sciences, Mount Sinai School of Medicine, New York, NY

Translating Cancer Gene Discovery to the Clinic

 

Thomas J. Hudson, MD (Invited Speaker)

President and Scientific Director, Ontario Institute for Cancer Research, Toronto, Ontario, Canada

Genome Variation and Cancer

Mark A. Labow, PhD (Invited Speaker)

Executive Director, Developmental and Molecular Pathways, Novartis Institute for Biomedical Research, Cambridge, MA

Utilizing Functional Genomics to Define Mechanism of Action and Potential Biomarkers for Novel Therapeutics

12:30 p

Lunch

2:00 p

 

James R. Lupski, MD, PhD (Invited Speaker)

Cullen Professor and Vice Chair, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX

Genomic Disorders: Mechanisms and Assays for CNVs in Human Disease

 

James L. Kennedy, MD (Invited Speaker)

Director, Neuroscience Research Department; Head, Psychiatric Neurogenetics Section, Centre for Addiction & Mental Health; and Professor, Department of Psychiatry and Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada

Pharmacogenetic Prediction of Side Effects to Psychiatric Medications

Francis J. McMahon, MD (Invited Speaker)

Chief, Genetic Basis of Mood and Anxiety Disorders Unit, National Institute of Mental Health, NIH, Bethesda, MD

Genetic Markers of Antidepressant Outcome: Lessons from the STAR*D Study

3:45 p

Poster Session

5:45 p

Adjourn

Friday, January 30, 2009

8:15 a

Registration/ Continental Breakfast

8:45 a

Edward Abrahams, PhD  (Moderator)

Executive Director, Personalized Medicine Coalition, Washington DC

Panel Discussion:  Public Policy Issues that Surround the Development and Adoption of Personalized Medicine

Randy Burkholder  (Panelist)

Associate Vice President, Policy Pharmaceutical Research & Manufacturers of Amercia (PhRMA), Washington, DC

Pharmaceutical Research and Personalized Medicine: Key Policy Issues

Michael F. Christman, PhD (Panelist)

President, Chief Executive Officer, Coriell Institute for Medical Research, Camden, NJ

The Coriell Personalized Medicine Collaborative — an Evidenced–Based Study of the Clinical Utility of Genome Information

Gregory J. Downing, DO, PhD (Panelist)

Program Director, Personalized Health Care, Immediate Office of the Secretary, Department of Health and Human Services, Washington, DC

Establishing the Pathway to Personalized Health Care

10:15 a

Break

10:45 a

Linda Brzustowicz, MD (Invited Speaker)

Professor, Department of Genetics, Rutgers University, Piscataway, NJ

Uncovering the Genetic Architecture of Schizophrenia Risk

Mark Mintz, MD (Invited Speaker)

President & CEO, The Center for Neurological and Neurodevelopmental Health and the Clinical Research Center of New Jersey , Voorhees, NJ; Adjunct Associate Professor of Pediatrics and Neurology , University of Pennsylvania School of Medicine; Clinical Assistant Professor of Pediatrics, UMDNJ-New Jersey Medical School

Clinical Phenotyping and Diagnostic Testing Algorithms for Autism

Nadine Cohen, PhD (Invited Speaker)

Head of Pharmacogenomics and Senior Research Fellow, Johnson & Johnson Pharmaceutical Research & Development, Raritan, NJ

Pharmacogenomics in Drug Development: Challenges and Opportunities

12:30 p

Lunch

2:00 p

Randall W. Nelson, PhD (Invited Speaker)

President and CEO, Intrinsic Bioprobes Inc. and Research Professor and Director of the Molecular Biosignatures Analysis Unit, The Biodesign Institute, Arizona State University, Tempe, AZ

Identification of Disease-Associated Protein Heterogeneity

Raymond B. Birge, PhD (Invited Speaker)

Associate Professor, Department of Biochemistry, UMDNJ-New Jersey Medical School, Newark, NJ

Markers of Inflammatory Diseases

Daniel Fine, DMD (Invited Speaker)

Professor and Chairman, Department of Oral Biology and Director, Center for Oral Infectious Diseases, UMDNJ-New Jersey Dental School, Newark NJ

A Lactoferrin Single Nucleotide Polymorphism Influences a Shift in the Oral Microbial Ecology and the Manifestation of Disease in Humans

3:45 p

Adjourn

 

Faculty Profiles

Dr. Bocarsly

The NJMS Office of Research is delighted to announce the receipt of two NIH “Shared Instrumentation Grant Awards” recently awarded to Drs. David Lagunoff and Patricia Fitzgerald-Bocarsly

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